Mechanisms of Familial and UV-induced Melanoma
Abstract
Melanoma is the most common form of skin cancer in the United States. Melanoma is a disease where cancerous cells derive from melanocytes. Common melanoma susceptibility genes induce dysregulation in the mitogen-activated protein kinase (MAPK) pathway, phosphatase and tensin homolog (PTEN),and AKT expression. Melanoma can be induced through prolonged UV-radiation or familial diagnosis. This article aims to discuss the mechanisms of both familial and UV-induced melanomagenesis
Keywords:
- Keyword: Dermatology
- Keyword: Melanoma
- Keyword: UV-radiation
- Keyword: Familial melanoma
- Keyword: Molecular Biology
- Keyword: Susceptibility genes
How to Cite:
Hughes, J. D., (2025) “Mechanisms of Familial and UV-induced Melanoma”, Pursuit - The Journal of Undergraduate Research at the University of Tennessee 12(1). doi: https://doi.org/10.7290/pur12wcew
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